Endocrine Abstracts

ObjectiveIn this retrospective study we investigated the clinical and radiological characteristics, hormonal status and metabolic components of the patients with adrenal incidentaloma(AI). Additionally, we investigated whether tumor size or hormonal status changes during long-term follow-up and the effect of these on metabolic parameters.Methods: The data of 384 patients who were followed up with the diagnosis of AI between 2010 an...

Objectives: High-fructose corn syrup (HFSC) is used as an artificial sweetener. However, there is limited information about the metabolic effects. Fructose is implicated in the etiology of nonalcoholic fatty liver disease(NAFLD). Unfortunately, no therapy for NAFLD currently exists. The aim of this study was to investigate the hepatic lesion induced by chronic HFCS consumption and the protective effects of alpha-lipoic acid (ALA) on hepatic pathology.Met...

Introduction: Gestational diabetes mellitus (GDM) is a condition that occurs during pregnancy when the body cannot produce enough insulin to handle the effects of a growing baby and changing hormone levels. Numerous studies reported that an increased risk of GDM among women who are overweight or obese compared with lean or normal-weight women.Methods/design: The purpose of this study is to compare anthropometric and biochemical parameters in postmenopaus...

Introduction: It is well known association between cardiovascular disease and PCOS. Approximately 17–43% of women with PCOS have hyperprolactinemia. Increased levels of prolactin often associated with an increased risk for thromboembolic events, but underline pathophisiological mechanism still unknown. The strong association between hyperprolactinemia and platelet aggregation is well known. Platelets play a key role in the development of atherothrombosis, a major contribu...

Introduction: Night eating syndrome (NES) is an eating disorder associated with obesity, characterized by a delayed pattern of food intake in which recurrent episodes of nocturnal eating and/or excessive food consump-tion occur after the evening meal. (1) Studies showed significant weight gain among patients with NES.However, the underlying reason is still controversial.The aim of this study is to investigate the body composition and energy metabolism in patients with NES....

Introduction: ACTH deficiency is a rare disease with non-specific symptoms such as anorexia, fatigue and weight loss. Due to these silent symptoms the disease is easily overlooked and may escape detection for a long time, especially in elderly patient.Case: 67-year-old female patient applied with complaints of fatigue. Bilateral adrenal adenoma was detected during ultrasonographic evaluation and and patient was consulted to endocrinology clinic Her perso...

Background: Studies have shown that smoking may increase the risk of pancreatic disorders. This study aimed to evaluate the oxidative stress status, biochemical, pathological and immunohistochemical findings of rats exposed to the cigarette smoke, pathogenesis of smoking related pancreatic damage and usability of Alpha Lipoic Acid (ALA) for amelioration of cigarette’ harmful effects on rat pancreas.Methods: Twenty eight female, Sprague Dawley rats w...

Pituitary tumors are the most frequent intracranial neoplasm, affecting 11 000 of the world wide population. However metastases in this location are rare and uncommon presentation of systemic malignancy. Although diabetes insipidus secondary to cancer metastasis to the pituitary gland is a common manifestation, anterior pituitary failure is rare. We present a −57-year-old man with hypopituitarism secondary to pituatry metastasis from lung cancer.Ca...

Introduction: Thyroid nodule is a common finding in neck ultrasonography performed in adult age group. Appropriate management of patients with thyroid nodules accuretly is very difficult process. Fine needle aspiration biopsy (FNAB), is the traditional invasive method used to identify nodules. Investigations are continuing for noninvasive techniques. Elastography is the imaging new technic,to evaluate the nodules. Aim of this study to evaluate the results of FNAB and elastogra...

Introduction: Acute myeloid leukemia infiltrates the CNS in up to 50% of cases. In contrast, the infiltration of the pituitary gland by leukemia cells is unusual. To date, AML presenting with central diabetes insipidus (CDI) has been rarely reported. Here, we present a patient with AML (subtype clasification is proceeding) presenting with panhypopituitarism and CDI.Case report: A 37-years-old man, with no significant past medical history, presented to Em...